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Sun, Nov 18, 2018
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  2. We’re Reimagining Our Travel Journalism. Tell Us What You’d Like to See.
  3. Why 536 AD was the worst year to be alive
  4. Great Pyramid of Giza: Egyptian Pharaoh ‘HIDDEN in secret chamber’
  5. How will Trump take Amazon move? ‘He will think Bezos made this decision to stick it to him.’
  6. SHARE PUNT OF THE WEEK: Pub chain Fuller’s
  7. Live Statue of Unity: Special coverage of inaugural of world’s tallest statue
  8. Jessie J ‘disappointed’ with fan comparisons to Channing Tatum’s ex Jenna Dewan
  9. NHS system error puts lives at risk as nearly 50,000 women are not sent screening letters
  10. Chiefs fans frustrated after NFL moves game vs. Rams from Mexico City to Los Angeles
  11. Bullets that don’t miss, weaponized insects and more: Innovations from DARPA, America’s secret lab
  12. Alien news: Oregon woman stunned as ’15 shape-changing UFOs’ appear
  13. Mattis heads to US-Mexico border to visit troops awaiting migrant caravan
  14. Telematics insurance has helped cut young driver casualties by a third
  15. Budget 2015 headlines in 4 minutes – BBC News
  16. Michael Douglas says famous dad Kirk Douglas told him his acting debut was ‘absolutely terrible’
  17. Now US regulators vow to ban menthol cigarettes
  18. West Ham midfielder Robert Snodgrass insists his side should be doing better this season
  19. Christian women in Ireland don’t believe in limbo anymore, survey finds
  20. Ancient Egypt bombshell: Shock evidence pyramids built 5,500 years early
  21. California’s Rohrabacher not conceding despite media’s call of Democrat victory
  22. Launch of dedicated ‘Poppy’ bank accounts gives boost for Armed Forces
  23. India’s campaigning Miss World – BBC News
  24. Red Dead Online release date: When does Red Dead Redemption 2 multiplayer come out? | Gaming | Entertainment
  25. Wynn Resorts shares fall 12 percent as it misses earnings estimates
  26. Several former NFL players win midterm races
  27. Facebook starts shipping Portal smart displays
  28. Alien news: Nazi technology ‘exposed as floating bell stuns locals’
  29. Prince Charles won’t speak out when he becomes king
  30. How do I vote if I own shares in a nominee account not paper?
  31. What if UK PM refused to allow another Scottish referendum? BBC News
  32. Legendary stuntwoman Kitty O’Neil dead at 72
  33. Opioid overdoses killed 200 Americans a DAY last year, DEA report reveals
  34. Transfer news LIVE: Neymar to Barcelona shock, Man Utd wage problem, Chelsea swap deal | Football | Sport
  35. Victorian street demolished in Second World War is found in Cornwall
  36. NASA spots huge ‘thermal anomaly’ in Atlantic Ocean sparking frenzy
  37. Avenatti stars in ‘avenging angel’ role
  38. Property prices pushed down by over valuations, a lack of supply and Brexit, say estate agents
  39. CEO Mette Hoffmann Meyer on BBC World News
  40. Jason Aldean, wife Brittany Kerr reveal daughter’s name at baby shower
  41. Phoenix Coldon’s mysterious disappearance perplexes retired officer in new doc: ‘I want to help bring some closure’
  42. Marsha Blackburn leads Phil Bredesen
  43. Is Russia still meddling in US politics? – BBC News
  44. Raheem Sterling arrives for Manchester City training with ‘Fully Paid’ hat
  45. Where to see the best fall foliage across the country
  46. New ‘sensitive’ cervical cancer screening could save women from smear tests after 55
  47. Alien news: UFO spotted ‘taking off from the moon’ in BOMBSHELL clip
  48. Sky finally launches Netflix via its Sky Q boxes
  49. John Schneider reveals ‘Dukes of Hazzard’ memories, weighs in on Tom Wopat troubles
  50. Angela Merkel’s political challenges – BBC News
  51. Essential Gear for Traveling Solo
  52. Paul Zimmerman, acclaimed NFL writer known as ‘Dr. Z,’ dead at 86
  53. Britain’s first double hand transplant patient can now open his door
  54. Ghost news: Man is ‘followed around haunted house by girl in a cape’
  55. Florida mayor accused of asking resident for sex in exchange for neighborhood speed bumps
  56. Is Mike Ashley King of the High Street? As he bags Evans Cycles, what else is in his retail empire?
  57. Kate Middleton reveals royal rule for Prince George, Princess Charlotte
  58. Trump says ‘no’ to migrants: BBC News Review
  59. Manchester United stars arrive for training ahead of Bournemouth clash
  60. NYC airport workers to earn nation’s highest minimum wage
  61. Costa Coffee stores BAN under 16s from buying caffeinated drinks
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  63. Savills forecasts house prices will rise 15% in five years
  64. ‘Broad City’ star Ilana Glazer’s political event canceled after vandals write ‘kill all Jews’ inside synagogue
  65. World’s Tallest Statue Cost $420 Million, Tivals The Space Needle | NBC News
  66. The home of Bollywood has much to offer travelers
  67. NHL player Evander Kane facing $6M lawsuit as ex-girlfriend claims he reneged on $3M abortion payment
  68. Woman, 24, whose IBS left her looking ‘nine months pregnant’ is now a slim size 10
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  70. Dumbo octopus monster SPOTTED by deep-sea EV Nautilus explorers
  71. Who is George Soros? – BBC News
  72. Dad creates VR world to help daughter – BBC News
  73. David Foster and Katharine McPhee show some PDA at Beverly Hills event
  74. DNA testing websites are ‘scaring women into asking for breast removal surgery’
  75. It Might Not Be a Drinking Problem, but It’s Definitely a Problem
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  77. Leicester helicopter crash: Schmeichel ‘stopped by police as he ran at burning helicopter’ | Football | Sport
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  79. Meghan Markle, Prince Harry breaking royal protocol? 7 times the couple strayed from tradition
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  81. Hope for the millions of women with endometriosis as scientists edge one step closer to a ‘cure’
  82. Maxine Waters, Schiff among high-profile Dems poised to control committees if House flips
  83. Google Earth spots ‘secret spy plane’ in US military base near Area 51
  84. Parents are paying out thousands for their children to go on school trips
  85. The new MacBook Air makes it near impossible to eavesdrop
  86. Just FIVE percent of US children are meeting the recommended amount of weekly physical activity
  87. Brazilian airline Gol to offer premium class with no middle seats
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  91. Vanessa Trump files for divorce from Donald Trump Jr
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  95. Fighting the flu? This technology tries to help you get well faster
  96. Google hopes AI can predict heart disease by looking at retinas
  97. This startup wants to create a 3D-printed heart
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  100. How to Create an Exceptional Omnichannel Retail Experience
  101. Jimmie Johnson Mired in Career Worst 28-Race Losing Streak
  102. South Carolina Advances With 79-63 Win Over Buffalo
  103. Thomas Nears No. 1 With Another Short Round in Match Play
  104. Austin serial bomber: Self-described psychopath left behind unemotional trail of murder
  105. ‘Half my family is gone’: Mom mourns Iowa family found dead at Mexico resort
  106. March for our Lives rallies happening in every U.S. state: ‘We’re here and coming to make a change’


Hope has been raised for millions of endometriosis sufferers as scientists have edged one step closer towards a cure. 

Researchers took stem cells from patients and managed to reprogram them to become healthy womb tissue in the lab.

Endometriosis occurs when the tissue that lines the uterus is found elsewhere in the body, such as the pelvis, fallopian tubes and sometimes even the eyes.  

When these cells break down during a woman’s period, it causes internal bleeding, which can cause agonising discomfort and infertility.

‘This is huge,’ senior author Dr Serdar Bulun, from Northwestern University, said. ‘We’ve opened the door to treating endometriosis.’

Scientists edge closer towards finding a cure for the painful disorder endometriosis (stock)

The researchers took ‘master’ stem cells from the skin and bone marrow of women with endometriosis.

These cells can be engineered to produce any cell or tissue the body needs to repair itself. 

Using hormonal treatments, the scientists reprogrammed the stem cells to become healthy endometrial cells in the lab after just two weeks. 

Endometrium is the name given to the womb lining.

The study was published in the journal Stem Cell Reports.  

Due to the cells being taken from patients themselves, there was no risk they would be rejected, the scientists said. 

Although stem cells have previously been turned into tissue found in the heart, liver and pancreas, this is the first study to show it can become uterus lining.

As well as benefiting women’s health, the scientists even believe their study could help combat the opioid crisis in the US, which President Trump has declared a public health emergency. 

‘These women with endometriosis start suffering from the disease at a very early age,’ Dr Bulun said.

‘So we end up seeing young high school girls getting addicted to opioids, which totally destroys their academic potential and social lives.’

The next step is to see if diseased endometrial cells can be reprogrammed to become healthy outside of the lab.  

WHAT IS ENDOMETRIOSIS?

Endometriosis occurs when cells in the lining of the womb are found elsewhere in the body. 

Each month, these cells react in the same way as those in the womb; building up, breaking down and bleeding. Yet, the blood has no way to escape the body.

Symptoms include pain, heavy periods and fatigue, as well as a higher risk of infertility, and bowel and bladder problems.

Its cause is unknown but may be genetic, related to problems with the immune system or exposure to chemicals.

Treatment focuses on pain relief and improving quality of life, which may include surgery or hormone treatment.

Source: Endometriosis UK

Endometriosis is a painful condition that affects around 10 per cent of women.

In the same way the cells of the womb lining break down during a woman’s period, the cells that have traveled elsewhere in the body react in the same way.

However, this internal bleeding has no way of escaping, which leads to inflammation, pain and the formation of scar tissue.

Although endometriosis’ exact cause is unclear, it has been linked to cells in the uterus lining failing to properly respond to the hormone progesterone.

Progesterone thickens the lining of the womb in preparation for the implantation of a fertilised egg.

When progesterone levels fall, a woman has her period, with endometriosis sufferers also bleeding internally. 

The researchers, led by Dr Kaoru Miyazaki, found the reprogrammed cells responded well to progesterone.  

In the short term, endometriosis has been linked to painful periods and discomfort during sex.

Over the long term, it can cause infertility due to defective cells not properly responding to an embryo.

And, in rare cases, it can even lead to endometrial and ovarian cancer. 

Treatment options are limited and include surgery, hormone therapies and pain management. But none have long-term evidence of success.

Uterus transplants have been tried but run the risk of patients rejecting them.

The researchers believe this could be solved by ‘rebuilding’ the womb from a patient’s own cells. 

‘One day we hope to make a whole uterus using this cell-based treatment employing the patient’s own cells,’ Dr Bulun, who has been studying endometriosis for 25 years, said.

He added, however, this could be a long shot.  



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